Научная электронная библиотека
Монографии, изданные в издательстве Российской Академии Естествознания
Медведев В. Л., Ледванов М. Ю., Курзанов А. Н., Быков И. М.,
Литература к главе 1
α1. Abbate M., Zoja C., Rottoli D., Corna D., Tomasoni S., Remuzzi G. Proximal tubular cells promote fibrogenesis by TGF-beta1-mediated induction of peritubular myofibroblasts. Kidney Int 2002; 61: 2066-77.
2. Abdulkader, R.C., Yuki, M.M., Paiva, A.C., & Marcondes, M. (1988). Prolonged inhibition of angiotensin II attenuates glycerol-induced acute renal failure. Brazilian Journal of Medical and Biological Research, Vol. 21, № 2, pp. 233-239.
3. Adam R.M., Eaton S.H., Estrada C. et al. Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol Genomics. 2004; 15; 20(1): 36-44.
4. Agouni, A.; Sourbier, C.; Danilin, S.; Rothhut, S.; Lindner, V.; Jacqmin, D.; Helwig, J.J.; Lang, H.; Massfelder, T. Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B. Carcinogenesis 2007, 28, 1893–1901.
5. Akashi T., Muraishi Y., Mizuno I., Nagakawa O., Okumura A., Iwasaki M., Fuse H. Bladder cancer and penile cancer with high serum level of PTHrP: A report of two cases. Nishinihon Journal of Urology 1999; 61(5): 448-451.
6. Al Kalbani N., Frieling M., Teh J.C., Harvey E., Geary D.F. Idiopathic hypercalcemia in infants with renal dysplasia. Clin Nephrol. 2011; 75(5): 466–71.
7. Allison, E.T., Drucker, D.J. Parathyroid hormone-like peptide shares features with members of the early response gene family: Rapid induction by serum, growth factors, and cycloheximide. Cancer Res. 1992; 52: 3103–3109.
8. Allred, A.J., Chappell, M.C., Ferrario, C.M., & Diz, D.I. (2000). Differential actions of renal ischemic injury on the intrarenal angiotensin system. American Journal of Physiology. Renal Physiology, Vol. 279, № 4, (October 2000), pp. F636-F645.
9. Amizuka N., Lee H.S., Kwan M.Y., Arazani A., Warshawsky H., Hendy G.N., Ozawa H., White J.H., Goltzman D. Cell-specific expression of the parathyroid hormone (PTH)/PTH-related peptide receptor gene in kidney from kidney-specific and ubiquitous promoters. Endocrinology. 1997 138: 469-81.
10. Ando T., Akiyoshi Katagiri, Ryo Nakayama, et al. Hypercalcemia associated with lymph node metastasis following radical cystectomy for bladder cancer. IJU Case Reports. 2018, Vol. 1, № 1, p. 25.
11. Ardura J.A., Rayego-Mateos, S., Ramila D., Ortega-Ruiz, M., & Esbrit P. (2010). Parathyroid hormone-related protein promotes epithelial-mesenchymal transition. Journal of the American Society of Nephrology. 2010; 21(2): 237-248.
12. Ardura, J.A., Berruguete, R., Ramila, D., Alvarez-Arroyo, V., Esbrit, P. (2008). Parathyroid hormone-related protein interacts with vascular endothelial growth factor to promote fibrogenesis in the obstructed mouse kidney. American Journal of Physiology. Renal Physiology, Vol. 295, № 2, (June 2008), pp. F415-F425.
13. Ardura, J.A., Sanz, A.B., Ortiz, A. et al. Parathyroid hormone–related protein protects renal tubuloepithelial cells from apoptosis by activating transcription factor Runx2. Kidney Int. 2013; 83: 825–834.
14. Asahi, Y., Kubonishi, I., Imamura, J. et al. Establishment of a clonal cell line producing granulocyte colony-stimulating factor and parathyroid hormone-related protein from a lung cancer patient with leukocytosis and hypercalcemia. Jpn. J. Cancer Res. 1996; 87: 451-458.
15. Atchison D.K., Westrick E., David L. Szandzik, Kevin L. Gordish, William H. Beierwaltes. Parathyroid hormone-related protein stimulates plasma renin activity via its anorexic effects on sodium chloride intake. American Journal of Physiology. Endocrinology and Metabolism. 2012; 303: 4: E457-463. 10.1152/ajpendo.00020.2012.
16. Aya K., Tanaka H., Ichinose Y., Kobayashi M., Seino Y. Expression of parathyroid hormone-related peptide messenger ribonucleic acid in developing kidney. Kidney Int. 1999; 55(5): 1696–1703.
17. Bagchus W.M., Jeunink M.F., Elema J.D. The mesangium in anti-Thy-1nephritis.Influx of macrophages, mesangial cell hypercellularity, andmacromolecular accumulation.Am J Pathol. 1990; 137: 215–223.
18. Baker A.J., Mooney A., Hughes J., Lombardi D., Johnson R.J., Savill J. Mesangial cell apoptosis: the major mechanism for resolution ofglomerular hypercellularity in experimental mesangial proliferativenephritis. J Clin Invest. 1994; 94: 2105–2116.
19. Basnakian A.G., Kaushal, G.P., & Shah, S.V. (2002). Apoptotic pathways of oxidative damage to renal tubular epithelial cells. Antioxidant & Redox Signaling, Vol. 4, № 6, (2002), pp. 915-924.
20. Benigni, A. and Remuzzi, G. Glomerular protein trafficking and progression of renal disease to terminal uremia. Semin Nephrol. 1996; 16: 151–159.
21. Bick R.L. Cancer-associated thrombosis. N Engl J Med. 2003; 349:109–111. doi: 10.1056/NEJMp030086.
22. Bonventre, J.V. (2003). Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. Journal of the American Society of Nephrology, Vol. 14, № Suppl 1, (2003), pp. S55-S61.
23. Border W.A., Noble N.A. TGF-beta in kidney fibrosis: a target for gene therapy. Kidney Int 1997; 51: 1388-96.
24. Bosch R.J., Ortega A., Izquierdo A., I. Arribas, J. Bover, and P. Esbrit, A transgenic mouse model for studying the role of the parathyroid hormone-related protein system in renal injury // Journal of Biomedicine and Biotechnology, vol. 2011, Article ID 290874, 7 pages, 2011.
25. Bosch R.J., Arenas M.I., Romero M., Nuria Olea, Adriana Izquierdo, Arantxa Ortega, Esperanza Velez, Jordi Bover, Juan C. Ardura,Esbrit P. (10th 2012). Parathyroid Hormone-Related Protein as a Mediator of Renal Damage: New Evidence from Experimental as well as Human Nephropathies, Chronic Kidney Disease and Renal Transplantation, Manisha Sahay, IntechOpen, DOI: 10.5772/25518.
26. Bosch R.J., Rojo-Linares P., Torrecillas-Casamayor G., Iglesias-Cruz M.C., Rodriguez-Puyol D. and Rodriguez-Puyol M. (1999) Effects of parathyroid hormone-related protein on human mesangial cells in culture. Am. J. Physiol.1999; 277, E990–E995.
27. Bosch R.J., Rodriguez-Puyol D., Bover J., Rodriguez-Puyol M. Parathyroid Hormone-Related Protein: Roles in the Glomerulus. Exp Nephrol 7(3): 212-216, 1999. DOI: 10.1159/000020604.
28. Bottinger E.P. TGF-beta in renal injury and disease. Semin. Nephrol. 2007; 27: 309–320.
29. Bowden S.J., Emly J.F., Hughes S.V., Powell G., Ahmed A., Whittle M.J., Ratcliffe J.G., Ratcliffe W.A. Parathyroid hormone-related protein in human term placenta and membranes. J Endocrinol. 1994 Aug; 142(2): 217-24.
30. Brading A.F. A myogenic basis for the overactive bladder. Urology. 1997 Dec; 50(6A Suppl): 57-67; discussion 68-73.
31. Braun K., Atmanspacher F., Schreckenberg R., Grgic I., Schluter K-D., Effect of free running wheel exercise on renal expression of parathyroid hormone receptor type 1 in spontaneously hypertensive rats, Physiological Reports. 2018; 6(17): e13842. doi.org/10.14814/phy2.13842.
32. Burtis W.J., Wu T., Bunch C. et al. Identification of a novel 17,000-dalton parathyroid hormone-like adenylatecyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy. J Biol Chem. 1987; 262: 7151–7156.
33. Burton PB., Moniz C., Quirke P., Tzannatos C., Pickles A., Dixit M., Triffit JT., Jueppner H., Segre GV., Knight D.E. Parathyroid hormone-related peptide in the human fetal uro-genital tract. Mol. Cell. Endocrinol. 1990; 69: R13–R17.
34. Burton P.B.J., Moniz C., Quirke P., Malik A., Bui T.D., Jueppner H., Segre G.V., Knight D.E.: Parathyroid hormone-related peptide: Expression in fetal and neonatal development. J Pathol. 1992; 167: 291-296.
35. Burton, P.B.J., Moniz, C., Knight, E. Parathyroid hormone-related peptide can function as an autocrine growth factor in human renal cell carcinoma. Biochem Biophys Res Commun. 1990; 167: 1134–1138.
36. Campos R.V., Asa S.l., Drucker D.J. Immunocytochemical localization of parathyroid hormone-like peptide in the rat fetus. Cancer Res. 1991; 51: 6351–6357.
37. Canario A.V.M., Rotllant J., Fuentes J., Guerreiro P.M., Rita Teodosio H., Power D.M., Clark M.S. Novel bioactive parathyroid hormone and related peptides in teleost fish. FEBS Lett.2006, 580: 291–299.
38. Cardoso J.C., Felix R.C., Power D.M. Nematode and arthropod genomes provide new insights into the evolution of class 2 B1 GPCRs. PLoS One (2014) 9: e92220. doi:10.1371/journal.pone.0092220.
39. Cebrian, A., Garcia-Ocana, A., Takane, K.K., Sipula, D., Stewart, A.F., & Vasavada, R.C. (2002). Overexpression of parathyroid hormone-related protein inhibits pancreatic beta-cell death in vivo and in vitro. Diabetes, Vol. 51, № 10, (2002), pp. 3003-3013
40. Chaudhary U.B., Milling D.L., Bissada N.K. Transitional cell carcinoma of the bladder producing parathyroid hormone-related protein (PTHrP). Can J Urol 2004; 11(1): 2136-8.
41. Chevalier, R.L. Obstructive nephropathy: towards biomarker discovery and gene therapy. Nature Clinical Practice. Nephrology. 2006; 3(2): 157-168.
42. Clemens T.L., Cormier S., Eichinger A., Endlich K., Fiaschi-Taesch N., Evelyne Fischer, Peter A Friedman, Andrew C Karaplis, Thierry Massfelder, Jerome Rossert, Klaus-Dieter Schluter, Caroline Silve, Andrew F Stewart, Karen Takane, Jean-Jacques Helwig. Parathyroid hormone-related protein and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets. Br J Pharmacol. 2001 Nov; 134(6): 1113–1136. doi: 10.1038/sj.bjp.0704378.
43. Clement P.B., Young R.H., Scully R.E. Clinical syndromes associated with tumors of the female genital tract. Semin Diagn Pathol. 1991; 8(4): 204–233.
44. Cramer S.D., Peehl D.M., Edgar M.G., Wong S.T., Deftos L.J., Feldman D. Parathyroid hormone-related protein (PTHrP) is an epidermal growth factor-regulated secretory product of human prostatic epithelial cells // Prostate. 1996; 29: 20-29.
45. Cros M., Silve C., Graulet A-M., Morieux C., Urena P., de Vernejoul M-C., Bouizar Z. Estrogen Stimulates PTHrP But Not PTH/PTHrP Receptor Gene Expression in the Kidney of Ovariectomized Rat. Journal of Cellular Biochemistry.1998; 70(1): 84–93.
46. Czykier, E., Zabel, M., & Surdyk-Zasada, J. (2001). Immunolocalization of PTHrP in the European bison and pine vole testis and epididymis. Folia histochemica et cytobiologica, 39 2, 57-61.
47. Daifotis A.G., Weir E.C., Dreyer B.E., Broadus AE., Stretch-induced parathyroid.
48. Daifotis A.G., Weir E.C., Dreyer B.E., Broadus AE., Stretch-induced parathyroidhormone-related peptide gene expression in the rat uterus. J Biol Chem. 1992; 25; 267(33): 23455-8.
49. Danilin, S.; Sourbier, C.; Thomas, L.; Rothhut, S.; Lindner, V.; Helwig, J.J.; Jacqmin, D.; Lang, H.; Massfelder, T. von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR. Carcinogenesis 2009, 30, 387–396.
50. De Miguel, F., Garcia-Canero, R., and Esbrit, P. Copurification of calcium transport-stimulating and DNA synthesis-stimulating agents with parathormone-like activity isolated from the hypercalcemic strain of the Walker 256 tumor. Eur J Cancer. 1991; 27: 1022–1026.
51. Drake M.J., Hedlund P., Harvey I.J. et al. Partial outlet obstruction enhances modular autonomous activity in the isolated rat bladder. J Urol. 2003; 170(1): 276-279.
52. Ebeling P.R., Adam W.R., Moseley J.M., Martin T.J. Actions of synthetic parathyroid hormone-related protein (1-34) on the isolated rat kidney..J Endocrinol. 1989 Jan; 120 (1): 45-50.
53. Eddy, A.A. Interstitial nephritis induced by protein-overload proteinuria. Am J Pathol. 1989; 135: 719–733.
54. Eddy, A.A., Giachelli, C.M. Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria. Kidney Int. 1995; 47: 1546–1557.
55. Egido J. Vasoactive hormones and renal sclerosis. Kidney International, Vol. 49, № 2, (1996), pp. 578-597.
56. Emly J.F., Gregory J., Bowden S.J., Ahmed A., Whittle M.J., Rushton D.I., Ratcliffe W.A. Immunohistochemical localization of parathyroid hormone-related protein (PTHrP) in human term placenta and membranes. Placenta. 1994; 15(6): 653-660.
57. Endlich K., Massfelder T., Helwing J.J., Steinhausen M. Vascular effects of parathyroid hormone and parathyroid hormone-related protein in the split hydronephrotic rat kidney. J. Physiol.(Lond) 1995; 483 :481–490.
58. Endlich N., R. Nobiling, W. Kriz, K. Endlich, Expression and signaling of parathyroid hormone-related protein in cultured podocytes, Experimental Nephrology, vol. 9, № 6, pp. 436–443, 2001.
59. Esbrit P., Ramila D., Ardura J.A., Ortega A., Romero M., Bosch R.J.: Role of PTHrP in renal pathophysiology. In: Novel Aspects of PTHrP Physiopathology, edited by Luparello C, editor. New York, Nova Science Publishers, 2007: 95–113.
60. Esbrit P., Egido J. The emerging role of parathyroid hormone-related protein as a renal regulating factor. Nephrol. Dial. Transplant. 2000; 15 (8): 1109-1111.
61. Esbrit P., Santos S., Ortega A., Fernandez-Agullo T., Velez E., Troya S. et al. (2001) Parathyroid hormone-related protein as a renal regulating factor. From vessels to glomeruli and tubular epithelium. Am. J. Nephrol. 2001 21(3), 179–184.
62. Esteban, V., Lorenzo, O., Ruperez, M. et al. Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. J Am Soc Nephrol. 2004; 15: 1514–1529.
63. Fan, J.M., Ng, Y.Y., Hill, P.A., Nikolic-Paterson, D.J., Mu, W., Atkins, R.C., & Lan, H.Y. Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney International, Vol. 56, № 4, (1999), pp. 1455-1467.
64. Feng C.C., Ding G.X., Song N.H., Li X., Wu Z., Jiang H.W., Ding Q. Paraneoplastic hormones: parathyroid hormone-related protein (PTHrP) and erythropoietin (EPO) are related to vascular endothelial growth factor (VEGF) expression in clear cell renal cell carcinoma. Tumour Biol. 2013 Dec; 34(6): 3471-6. doi: 10.1007/s13277-013-0924-7.
65. Ferguson J.E., Gorman J.V., Bruns D.E., Weir E.C., Burtis W.J., Martin T.J. and Bruns M.E.: Abundant expression of parathyroid hormone-related protein in human amnion and its association with labor. Proc Natl Acad Sci USA.1992; 89: 8384-8388.
66. Fiaschi-Taesch N., Endlich N., Massfelder T., Endlich K., Stewart A.F., Helwig J.J. 1998 Renovascular parathyroid hormone-related protein in spontaneously hypertensive rats: dilator or trophic factor? Kidney Int. 1998; Suppl 67: S207-210.
67. Fiaschi-Taesch, N.M., Santos, S., Reddy, V., Van Why, S.K., Philbrick, W.F., Ortega, A., Esbrit, P., Orloff, J.J., & Garcia-Ocana, A. Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor. Journal of the American Society of Nephrology, Vol. 15, № 1, (2004), pp. 112-125.
68. Flanagan J.A., Power D.M., Bendell L.A., Guerreiro P.M., Fuentes J., Clark M.S., Canario A.V., Danks J.A., Brown B.L., Ingleton P.M. Cloning of the cDNA for sea bream (Sparus aurata) parathyroid hormone-related protein. Gen Comp Endocrinol.2000, 118: 373–382.
69. Fritsch S., Lindner V., Welsch S., Massfelder T., Grima M., Rothhut S., Barthelmebs M., Helwig J.J. Intravenous delivery of PTH/PTHrP type 1 receptor cDNA to rats decreases heart rate, blood pressure, renal tone, renin angiotensin system, and stress-induced cardiovascular responses. J Am Soc Nephrol 15: 2588–2600, 2004
70. Funk J.L., Moser A.H., Strewler G.J., Feingold K.R., Grunfeld C. Parathyroid hormone-related protein is induced during lethal endotoxemia and contributes to endotoxin-induced mortality in rodents. Mol. Med. 1996; 2: 204–210.
71. Funk, J.L. (2001). A role for parathyroid hormone-related protein in the pathogenesis of inflammatory/autoimmune diseases. International Immunopharmacology, Vol. 1, № 6, (2001), pp. 1101-1121.
72. Galbraith, S.C., Van Why, S., Zager, R., Siegel, N., and Orloff, J.J. Parathyroid hormone-related protein (PTHrP) expression is upregulated in renal proximal tubule cells in response to in vitro tubular injury. (abstract) J Bone Miner Res. 1996; 11: S411.
73. Garcia-Ocana A., Galbraith S.C., Van Why S.K., Yang K., Golovyan L., Dann P, Zager R.A., Stewart A.F., Siegel N.J., Orloff J.J.: Expression and role of parathyroid hormone-related protein in human renal proximal tubule cells during recovery from ATP depletion. J Am Soc Nephrol 10: 238–244, 1999.
74. Garcia-Ocana A., Gomez-Casero E., Penaranda C., Esbrit P. Parathyroid hormone-related protein increases DNA synthesis in proximal tubule cells by cyclic AMP- and protein kinase C-dependent pathways. Life Sci. 1998; 62(25): 2267-73.
75. Garcia-Ocana, A., De Miguel, F., Penaranda, C., Albar, J.P., Sarasa, J.L., Esbrit, P. Parathyroid hormone-related protein is an autocrine modulator of rabbit proximal tubule cell growth. J Bone Miner Res. 1995; 10(12): 1875–1884.
76. Garcia-Ocana, A., Gomez-Casero, E., Penaranda, C., Sarasa, J.L., & Esbrit, P. (1998). Cyclosporine increases renal parathyroid hormone-related protein expression in vivo in the rat. Transplantation, Vol. 65, № 6, (1998), pp. 860-863.
77. Gomez-Garre, D., Largo, R., Soto, K., Tejera, N., and Egido, J. Overload proteinuria elicits nuclear factor ?;B activation in tubular epithelial cells: Role of angiotensin II and endothelin-1. (abstract) J Am Soc Nephrol. 1998; 9: 400A.
78. Gomez-Garre, D., Largo, R., Tejera, N. et al. Activation of NF-kappaB in tubular epithelial cells of rats with intense proteinuria: role of angiotensin II and endothelin-1. Hypertension. 2001; 37: 1171–1178.
79. Gore-Hyer, E., Shegogue, D., Markiewicz, M., Lo, S., Hazen-Martin, D., Greene, E.L., Grotendorst, G., & Trojanowska, M. (2002). TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells. American Journal of Physiology. Renal Physiology, Vol. 283, № 4, (October 2002), pp. F707-F716.
80. Gotoh A., Kitazawa S., Mizuno Y. et al. Common expression of parathyroid hormone-related protein and no correlation of calcium level in renal cell carcinomas // Cancer. – 1993. – 71. – P. 2803-6.
81. Grande, M., Frazen, A., Karlsson, J.O., Ericson, L.E., Heldin N.E., & Nilsson, M. Transforming growth factor-beta and epidermal growth factor synergistically stimulate epithelial to mesenchymal transition (EMT) through a MEK-dependent mechanism in primary cultured pig thyrocytes. Journal of Cell Science, Vol. 115, № Pt 22, (r 2002), pp. 4227-4236.
82. Grob F., Zambrano P., Ibarra X., Reyes M.L. Parathyroid hormone-independent hypercalcemia in an infant with renal dysplasia: possible role of PTHrP. J Pediatr Endocrinol Metab. 2013; 26(3–4): 365–7.
83. Gross M.L., Ritz E., Schoof A. et al., Comparison of renal morphology in the Streptozotocin and the SHR/N-cp models of diabetes, Laboratory Investigation, vol. 84, № 4, pp. 452–464, 2004.
84. Guenther, H.L., Hofstetter, W., Moseley, J.M., Gillespie, M.T., Suda, N., and Martin, T.J. Evidence for the synthesis of parathyroid hormone-related protein (PTHrP) by nontransformed clonal rat osteoblastic cells in vitro. Bone. 1995; 16: 341–347.
85. Guijarro C., Egido J. Transcription factor-kappa B (NF-kappa B) and renal disease. Kidney Int. 2001; 59: 415–424.
86. Guillen C., Martinez, P., de Gortazar, A.R., Martinez, M.E., & Esbrit, P. (2002). Both N- and C-terminal domains of parathyroid hormone-related protein increase interleukin-6 by nuclear factor-kappa B activation in osteoblastic cells. Journal of Biological Chemistry, Vol. 277, № 31, (2002), pp. 28109-28117.
87. Guo Y., Zhang A., Ding Y., Wang Y., Yuan W. Genistein ameliorates parathyroid hormone-induced epithelial-to-mesenchymal transition and inhibits expression of connective tissue growth factor in human renal proximal tubular cells. Archives of Medical Science. 2013; 9(4): 724-730. doi:10.5114/aoms.2013.36929.
88. Hanada M., Feng .J, Hemmings BA.Structure, regulationandfunc-tionofPKB/AKT–amajortherapeutictarget. Biochim Biophys Acta. 2004; 1697: 3–16.
89. Harris, R.C., Martinez-Maldonado, M. (1995). Angiotensin II-mediated renal injury. Mineral and Electrolyte Metabolism, Vol. 21, № 4-5, (1995), pp. 328-335.
90. Hashitani H., Brading A.F., Suzuki H. Correlation between spontaneous electrical.
91. Hashitani H., Brading A.F., Suzuki H. Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder. Br J. Pharmacol. 2004; 141(1): 183-93.
92. Henderson, J.E., Amizuka, N., Warshawsky, H., Biasotto, D., Lanske, B.M., Goltzman, D., Karaplis, A.C. (1995). Nucleolar localization of parathyroid hormone-related peptide enhances survival of hondrocytes under conditions that promote apoptotic cell death. Molecular and Cell Biology, Vol. 15, № 8, (1995), pp. 4064-4075.
93. Hengst L., Reed S.I., Inhibitors of the Cip/Kip family, Current Topics in Microbiology and Immunology, vol. 227, pp. 25–41, 1997.
94. Hirasawa K., Kitamura T., Oka T., Matsushita H. Bladder tumor producing granulocyte colony-stimulating factor and parathyroid hormone related protein. J Urol 2002, 167: 2130. doi: 10.1016/S0022-5347(05)65104-X.
95. Hochane M., Raison D., Coquard C., Beraud C., Bethry A., Danilin S., Massfelder T., Barthelmebs M. Parathyroid hormone-related protein modulates inflammation in mouse mesangial cells and blunts apoptosis by enhancing COX-2 expression. Am J Physiol Cell Physiol. 2018.1; 314(2): C242-C253. doi: 10.1152/ajpcell.00018.2017.
96. Hochane M., Raison D., Coquard C., Beraud C., Danilin S., Bethry A., Massfelder T., Barthelmebs M.P. Parathyroid Hormone-Related Protein Contributes to Early Healing of Habu Snake Venom-Induced Glomerulonephritis in Mice. Am J Pathol. 2018; 188(4): 863-875. doi: 10.1016/j.ajpath.2017.12.012.
97. Hochane M., Raison D., Coquard C., Imhoff O., Massfelder T., Moulin B. et al. (2013) Parathyroid hormone-related protein is a mitogenic and a survival factor of mesangial cells from male mice: role of intracrine and paracrine pathways. Endocrinology 154, 853–864.
98. Hofle G., Gasser R.W., Buchfelder M., Fahlbusch R., Waldenberger P., Finkenstedt G. Elevated inferior petrosal sinus levels of PTHrP was reported in a patient with Cushing’s disease. Clin Endocrinol (Oxf) 2001; 54: 555–7.
99. Holt E.H., Lu C., Dreyer B.E., Dannies P.S., Broadus A.E.: Regulation of parathyroid hormone-related peptide gene expression by estrogen in GH4C1 rat pituitary cells has the pattern of a primary response gene. J Neurochem 62: 1239-1246, 1994.
100. Hongo, T., Kuofer, J., Enomoto, H., Sharifi, B., Giannella-Neto, D., Forester, J., Singer, F.R., Goltzman, D., Hendy, G.N., Pirola, C., Fagin, J.A., and Clemens, T.L. Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation. J Clin Invest. 1991; 88: 1841–1847.
101. Horiuchi N., Caulfield M.P., Fisher J.E. et al. Similarity of synthetic peptide from human tumor to parathyroid hormone in vivo and in vitro. Science 1987; 238: 1566–1568.
102. Hoshi S., Numahata K., Morozumi K., Katumata Y., Kuromoto A., Takai Y., Hoshi K., Bilim V., Sasagawa I. Bladder cancer metastasis producing beta-human chorionic gonadotropin, squamous cell carcinoma antigen, granulocyte-colony stimulating factor, and parathyroid hormone-related protein, IJU Case Reports. 2018; 2(1): 47-50.
103. Hu C., Sun L., Xiao L., Han Y., Fu X., Xiong X. et al. (2015) Insights into the mechanisms involved in the expression and regulation of extracellular matrix proteins in diabetic nephropathy. Curr. Med. Chem.22, 2858–2870.
104. Huang, H.C., Preisig P.A. (2000). G1 kinases and transforming growth factor-beta signaling are associated with a growth pattern switch in diabetes-induced renal growth. Kidney International, Vol. 58, № 1, (2000), pp. 162-172.
105. Humes H.D., Cieslinski D.A., Coimbra T.M., Messana .M., Galvao C.: Epidermal growth factor enhances renal tubule cell regeneration and repair and accelerates the recovery of renal function in postischemic acute renal failure. J Clin Invest 84: 1757-1761, 1989.
106. Humes, H.D., Lake, E.W., & Liu, S. (1995). Renal tubule cell repair following acute renal injury. Mineral and Electrolyte Metabolism, Vol. 21, № 4-5, (1995), pp. 353-365.
107. Hwang J.I., Moon M.J., Park S., et al. Expansion of secretin-like G protein-coupled receptors and their peptide ligands via local duplications before and after two rounds of whole-genome duplication. Mol Biol Evol. 2013; 30: 1119–30.
108. Ichikawa, I. and Harris, R.C. Angiotensin actions in the kidney: Renewed insight into the old hormone. Kidney Int. 1991; 40: 583–596.
109. Ikeda Y., Fry C., Hayashi F., et al. Role of gap junctions in spontaneous activity of the rat bladder. Am J Physiol Renal Physiol. 2007; 293(4): F1018-25.
110. Imamura M., Kanematsu A., Yamamoto S., et al. Basic fibroblast growth factor modulates proliferation and collagen expression in urinary bladder smooth muscle cells. Am. J Physiol Renal Physiol. 2007; 293(4): F1007–F1017.
111. Imamura M., Negoro H., Kanematsu A., et al. Basic fibroblast growth factor causes urinary bladder overactivity through gap junction generation in the smooth muscle. Am J Physiol Renal Physiol. 2009; 297(1): F46-54.
112. Ingleton P.M. Parathyroid hormone-related protein in lower vertebrates. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 2002, 132(1): 87-95.
113. Ito Y., Aten J., Bende R.J., et al. Expression of connective tissue growth factor in human renal fibrosis. Kidney Int 1998; 53: 853-61.
114. Iwamura M., Wu G., Abrahamsson P.A. et al. Parathyroid hormone-related protein is expressed by prostatic neuroendocrine cells. Urology. 1994b; 43: 667-674.
115. Iwamura M., Wu W., Muramoto M. et al. Parathyroid hormone-related protein is an independent prognostic factor for renal cell carcinoma // Cancer. – 1999; 86(6): 1028-34.
116. Iwano M., Plieth D., Danoff T.M., et al. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 2002; 110: 341-50
117. Izquierdo A., Lopez-Luna, P., Ortega, A., Romero, M., Gutierrez-Tarres, M.A., Arribas, I., Esbrit P., Bosch, R.J. (2006). The parathyroid hormone-related protein system and diabetic nephropathy outcome in streptozotocin-induced diabetes. Kidney International, Vol. 69, № 12, (2006), pp. 2171-2178.
118. Jiang, B.B., Morimoto, S., Fukuo, S., Hirotani, A., Tamatani, M., Nakahashi, T., Nishibe, A., Niinobu, T., Hata, S., Chen, S.Y., and Ogihara, T. Parathyroid hormone-related protein inhibits endothelin-1 production. Hypertension. 1996; 27: 360–363.
119. Jobert, A.S., Fernandes, I., Turner, G., Coureau, C., Prie, D., Nissenson, R.A., Friedlander, G., Silve, C. (1996). Expression of alternatively spliced isoforms of the parathyroid hormone (PTH)/PTH-related peptide receptor messenger RNA in human kidney and bone cells. Molecular Endocrinology, Vol. 10, № 9, (1996), pp. 1066-1076.
120. Jones E.A., Shahed A., Shoskes D.A.: Modulation of apoptotic and inflammatory genes by bioflavonoids and angiotensin II inhibition in ureteral obstruction. Urology 56: 346–351, 2000.
121. Joun H., Lanske B., Karperien M., Qian F., Defize L., Abou-Samra A. Tissue-specific transcription start sites and alternative splicing of the parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor gene: a new PTH/PTHrP receptor splice variant that lacks the signal peptide.Endocrinology. 1997; 138:1742–1749.
122. Kadin M.E., Cavaille-Coll M.W., Gertz R., J. Massague, S. Cheifetz, D. George, Loss of receptors for transforming growth factor β in human T-cell malignancies, Proceedings of the National Academy of Sciences of the United States of America, vol. 91, № 13, pp. 6002–6006, 1994.
123. Kalluri, R., Neilson E.G. (2003). Epithelial-mesenchymal transition and its implications for fibrosis. Journal of Clinical Investigation, Vol. 112, № 12, (December 2003), pp. 1776-1784.
124. Kamai T., Arai G., Takagi K., Kamai T., Arai G., Takagi K.: Granulocyte colony-stimulating factor and parathyroid hormone related protein producing bladder cancer. J Urol. 1999, 161: 1565-1566. 10.1097/00005392-199905000-00044.
125. Kashihara N., Sugiyama H., Makino H. Mechanisms for induction ofapoptosis and glomerular disease. NephrolDialTransplant.1999; 14 Suppl 1:52–54.
126. Kato T., Yasuda K., Iida H., Watanabe A., Fujiuchi Y., Miwa S., Imura J., Komiya A. Trousseau’s syndrome caused by bladder cancer producing granulocyte colony-stimulating factor and parathyroid hormone-related protein: A case report. Oncol Lett. 2016 Nov; 12(5): 4214–4218. doi: 10.3892/ol.2016.5152.
127. Katsumata S.-I., Masuyama R., Uehara M., Suzuki K. 2004. Decreased mRNA expression of the PTH/PTHrP receptor and type II sodium-dependent phosphate transporter in the kidney of rats fed a high phosphorus diet accompanied with a decrease in serum calcium concentration. Biosci. Biotech. Biochem. 68: 2484– 2489.
128. Kaushal, G.P., Basnakian, A.G., & Shah, S.V. (2004). Apoptotic pathways in ischemic acute renal failure. Kidney International, Vol. 66, № 2, (2004), pp. 500-506.
129. Kawane T., Saikatsu S., Akeno N., Abe M., Horiuchi N.. 1997. Starvation-induced increase in the parathyroid hormone/PTH related protein receptor mRNA of bone and kidney in sham-operated and thyroparathyroidectomized rats. Eur. J. Endocrinol. 137: 273– 280.
130. Kitazawa S., Kitazawa R., Fukase M. et al. Immunohistochemical evaluationof parathyroid hormone-related protein (PTHrP) in the uterine cervix. Int. J Cancer. 1992; 50: 731-735.
131. Kodous N., Filler G., Sharma A.P., Van Hooren T.A. PTHrP-related Hypercalcaemia in Infancy and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). Canadian journal of kidney health and disease (2015).2:21 DOI 10.1186/s40697-015-0052-y.
132. Kolm V., Sauer U., Olgemooller B. and Schleicher E.D. (1996) High glucose-induced TGF-β1 regulates mesangial production of heparan sulfate proteoglycan. Am. J. Physiol. 270, F812–F821.
133. Kontogiannis, J., & Burns, K.D. (1998). Role of AT1 angiotensin II receptors in renal ischemic injury. American Journal of Physiology. Renal Physiology, Vol. 274, № 1-Pt2, (1998), pp. F79-F90.
134. Kramann R., Schneider R.K. Parathyroid hormone–related protein and regulation of cell survival in the kidney. Kidney international. 2013; 83(5): 777–779.
135. Kriz, W., Grezt, N., & Lemley, K.V. (1998). Progression of glomerular diseases: is the podocyte the culprit?. Kidney International, Vol. 54, № 3, (1998), pp. 687-697.
136. Kuwahara, M., Inoshita, S., Nakano, Y., Terada, Y., Takano, Y., and Sasaki, S. 2007. Expression of bone type 1 PTH receptor in rats with chronic renal failure. Clin. Exp. Nephrol. 11: 34– 40.
137. Lang H., Endlich N., Lindner V., Endlich K., Massfelder T., Stewart A.F., Saussine C., Helwig J.J. Parathyroid hormone-related protein in rat penis: expression, localization, and effect on cavernosal pressure. Endocrinology. 1999 Sep; 140(9):4342-50.
138. Largo R., Gomez-Garre D., Santos S., Carlos Penaranda, Blanco J., Esbrit P. et al. Renal expression of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor in a rat model of tubulointerstitial damage. Kidney International, 1999; Volume 55, Issue 1, 82–90.
139. Largo, R., Gomez-Garre, D., Soto, K., Marron, B., and Egido, J. Angiotensin converting enzyme (ACE) is up-regulated in the proximal tubules of rats with protein-overload proteinuria. (abstract) J Am Soc Nephrol. 1997; 8: 501.
140. Law F., Bonjour J.P., Rizzoli R.: Transforming growth factor-beta: a down-regulator of the parathyroid hormone-related protein receptor in renal epithelial cells. Endocrinology 134: 2037–2043, 1994.
141. Law F., Rizzoli R., Bonjour J.P.: Transforming growth factor-beta modulates the parathyroid hormone-related protein-induced responses in renal epithelial cells. Endocrinology 133: 145–151, 1993.
142. Lee K., Mitsui R., Kajioka S. et al. Role of PTHrP and sensory nerve peptides in regulating the contractility of muscularis mucosae and detrusor smooth muscle in the guinea-pig bladder. The Journal of Urology. 2016; 196(4): 1287-1294. DOI: 10.1016/j.juro.2016.04.082.
143. Lee, F.T., Cao, Z., Long, D.M. et al. Interactions between angiotensin II and NF-kappaB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy. J Am Soc Nephrol. 2004; 15: 2139–2151.
144. Lee, K., Brown, D., Urena, P., Ardaillou, N., Ardaillou, R., Deeds, J., and Segre, G.V. Localization of parathyroid hormone/parathyroid hormone-related peptide receptor mRNA in kidney. Am J Physiol. 1996; 270: F186–F191.
145. Lewis M.P., Norman J.T. Differential response of activated versus nonactivated renal fibroblasts to tubular epithelial cells: a model of initiation and progression of fibrosis? Exp Nephrol 6: 132–143, 1998.
146. Lieberthal, W., Levine, J.S. (1996). Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. American Journal of Physiology. Renal Physiology Vol. 271, № 3 Pt2 (September 1996), pp. F477-F488.
147. Liu L., Qiu W., Wang H., et al. Sublytic C5b-9 complexes induceapoptosis of glomerular mesangial cells in rats with Thy-1 nephritisthrough role of interferon regulatory factor-1-dependent caspase 8activation. J Biol Chem. 2012; 287: 16410–16423.
148. Liu Y. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. Journal of the American Society of Nephrology. 2004; 15(1): 1-12.
149. Long, G.W., Misra, D.C., Juleff, R., Blossom, G., Czako, P.F., & Glover, J.L. (1993). Protective effects of enalaprilat against postischemic renal failure. Journal of Surgical Research, Vol. 54, № 3, (1993), pp. 254-257.
150. Lopez-Hernandez F.J. and Lopez-Novoa J.M. (2012) Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects. Cell Tissue Res. 347, 141–154.
151. Lorenzo O., Ruiz-Ortega, M., Esbrit, P., Ruperez, M., Ortega, A., Santos, S., Blanco, J., Ortega, L., & Egido, J. Angiotensin II increases parathyroid hormone-related protein (PTHrP) and the type 1 PTH/PTHrP receptor in the kidney. Journal of the American Society of Nephrology.2002; 13(6): 1595-1607.
152. Luparello C. Regulator of Life/Death Decisions by Tumor Cells with Potential Clinical Applications. Cancers. 2011; 3(1): 396-407; doi:10.3390/cancers3010396.
153. MacIsaac, R.J., Horne, R.S.C., Caple, I.W., Martin, T.J., & Wintour, E.M. (1993). Effects of thyroparathyroidectomy, parathyroid hormone, and PTHrP on kidneys of ovine fetuses. American Journal of Physiology – Endocrinology and Metabolism, 1993; 264(1): 37-44.
154. Maeda S., Sutliff R.l., Qian J., Lorenz J.N., Wang J., Tang H., Nakayama T., Weber C., Witte D., Strauch A.R., Paul R.J., Fagin J.A., Clemens T.L. Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility. Endocrinology. 1999; 140 :1815–1825.
155. Maeda Y., Nakazawa H., Yoshimura N., Okuda H., Oshima T., Ito F., Onitsuka S., Kihara T., Goya N., Toma H.: Bladder carcinoma presenting with hypercalcemia: a case report. Hinyokika Kiyo. 1997; 43: 137-140.
156. Manning B.D., Cantley L.C. AKT/PKBsignaling: navigatingdown-stream. Cell. 2007; 129: 1261–1274.
157. Marcinkowski, W., Zhang, G., Smogorzewski, M., and Massry, S.G. Elevation of [Ca2+] of renal proximal tubular cells and down-regulation of mRNA of PTH-PTHrP, V1a and AT1 receptors in kidney of diabetic rats. Kidney Int. 1997; 51: 1950–1955.
158. Martinez-Estrada, O.M., Culleres, A., Soriano, F.X., Peinado, H., Bolos, V., Martinez, F.O., Reina, M., Cano, A., Fabre, M., & Vilaro, S. (2006). The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells. Biochemical Journal, Vol. 394, № Pt2 (March 2006), pp. 449-457.
159. Martin-Ventura, J.L., Ortego, M., Esbrit, P., Hernandez-Presa, M.A., Ortega, L., Egido, J. (2003). Possible role of parathyroid hormone-related protein as a proinflammatory cytokine in atherosclerosis. Stroke, Vol. 34, № 7, (2003), pp. 1783-1789.
160. Massfelder T, Taesch N., Fritsch S., Eichinger A., Barthelmebs M., Stewart A.F., Helwig J.J. Type 1 parathyroid hormone receptor expression level modulates renal tone and plasma renin activity in spontaneously hypertensive rat. J Am Soc Nephrol 13: 639–648, 2002.
161. Massfelder T., Parekh N., Endlich K., Saussine C., Steinhausen M. and Helwig J.J. (1996) Effect of intrarenally infused parathyroid hormone-related protein on renal blood flow and glomerular filtration rate in the anaesthetized rat. Br. J. Pharmacol. 1996a; 118, 1995–2000.
162. Massfelder T., Taesch N., Endlich N., Eichinger A., Escande B., Endlich K., Barthelmebs M., Helwig J.J. Paradoxical actions of exogenous and endogenous parathyroid hormone-related protein on renal vascular smooth muscle cell proliferation: reversion in the SHR model of genetic hypertension. FASEB J. 2001; 15:707–718.
163. Massfelder T.; Lang, H.; Schordan, E.; Lindner, V.; Rothhut, S.; Welsch, S.; Simon-Assmann, P.; Barthelmebs, M.; Jacqmin, D.; Helwig, J.J. Parathyroid hormone-related protein is an essential growth factor for human clear cell renal carcinoma and a target for the von Hippel-Lindau tumor suppressor gene. Cancer Res. 2004, 64, 180–188.
164. Massfelder, T., Saussine, C., Simeoni, U., Enanga, B., Judes, C., and Helwig, J.J. Evidence for adenylyl cyclase-dependent receptors for parathyroid hormone (PTH)-related protein in rabbit kidney glomeruli. Life Sci. 1993; 53: 875–881.
165. Massfelder, T., Stewart, A.F., Endlich, K., Soifer, N., Judes, C., and Helwig, J.J. Parathyroid hormone-related protein detection and interaction with NO and cyclic AMP in the renovascular system. Kidney Int. 1996b; 50: 1591–1603.
166. Matsumoto K., Nakamura T. (2001). Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Internacional, Vol. 59, № 6, (2001), pp. 2023-2038, ISSN 0085-2538.
167. Matsuoka S., Miura Y., Kachi T., et al. Humoral hypercalcemia of malignancyassociated with parathyroid hormone-related protein producing transitional cellcarcinoma of the ureter. Intern Med 1994; 33: 107–9.
168. McCarthy C.J., Zabbarova I.V., Brumovsky P.R. et al. Spontaneous contractionsevoke afferent nerve firing in mouse bladders with detrusor overactivity. J Urol. 2009; 181(3): 1459-66.
169. McCuaig K.A., Lee H.S., Clarke J.C., Assar H., Horsford J., White J.H. Parathyroid hormone/parathyroid hormone related peptide receptor gene transcripts are expressed from tissue-specific and ubiquitous promoters. Nucleic Acids Res. 1995 23(11): 1948-55.
170. McKay N.G., Khong T.F., Haites N.E. and Power D.A. (1993) The effect of transforming growth factor beta 1 on mesangial cell fibronectin synthesis: increased incorporation into the extracellular matrix and reduced pI but no effect on alternative splicing. Exp. Mol. Pathol. 59, 211–224.
171. McRae S.N., Gilbert R., Deamant F.D., Reese J.H.: Poorly differentiated carcinoma of bladder producing granulocyte colony-stimulating factor and parathyroid hormone related protein. J Urol. 2001, 165: 527-528. 10.1097/00005392-200102000-00049.
172. Meng E., Young J.S., Brading A.F. Spontaneous activity of mouse detrusor smoothmuscle and the effects of the urothelium. Neurourol Urodyn. 2008; 27(1): 79-87.
173. Merryman, J.I., Deville, J.W., Werkmeister, J.R., Capen, C.C., and Rosol, T.J. Effects of transforming growth factor-beta on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro. Endocrinology. 1994; 134: 2424–2430.
174. Mezzano S.A., Ruiz-Ortega M., Egido J. Angiotensin II and renal fibrosis. Hypertension 2001; 38 (3 Pt 2): 635-638.
175. Mifsud, S.A., Allen, T.J., Bertram, J.F., Hulthen, U.L., Kelly, D.J., Cooper, M.E., WilkinsonBerka, J.L., Gilbert, R.E. (2001). Podocyte foot process broadening in experimental diabetic nephropathy: amelioration with renin-angiotensin blockade. Diabetologia, Vol. 44, № 4, (July 2001), pp. 878-882.
176. Miller S.B., Martin D.R., Kissane J., Hammerman M.R.: Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats.Am J Physiol.1994; 266: F129-F134.
177. Miller S.B., Martin D.R., Kissane J., Hammerman M.R.: IGF-I accelerates recovery from ischemic acute tubular necrosis in the rat. Proc Natl Acad Sci USA. 1992; 89: 11876-11880.
178. Morrissey J.J., Klahr S. Enalapril decreases nuclear factor kappa B activation in the kidney with ureteral obstruction. Kidney Int. 1997; 52: 926–933.
179. Moseley J.M., Kubota M., Diefenbach-Jagger H. et al. Parathyroid hormone-related protein purified from a human lung cancer cell line. PNAS 1987; 84: 5048–5052.
180. Moseley J.M., Hayman J.A., Danks J.A., Alcorn D., Grill V., Southby J., Horton M.A. Immunohistochemical detection of parathyroid hormone-related protein in human fetal epithelia. J. Clin.Endocrinol. Metab. 1991; 73: 478–484.
181. Muff R., Fischer J.A. Parathyroid hormone receptors in control of proximal tubule function. AnnuRev Physiol, 1992; 54: 67–79.
182. Muller, G.A., Markovic-Lipkovski, J., Frank, J., & Rodemann, H.P. The role of interstitial cells in the progression of renal diseases. Journal of the American Society of Nephrology.1992; 2 (10): S198-S205.
183. Murer H., Hernando N., Forster I. et al. Regulation of Na/Pi transporter in the proximal tubule. Annu Rev Physiol 2003; 65: 531–542.
184. Musso, M.J., Barthelmebs, M., Imbs, J.L., Plante, M., Bollack, C., Helwig, J.J. (1989a). The vasodilator action of parathyroid hormone fragments on isolated perfused rat kidney. Naunyn-Schmiedeberg’s Arch. Pharmacol. 1989a; 340: 246-251.
185. Musso, M.J., Plante, M., Judes, C., Barthelmebs, M., Helwig, J.J. Renal vasodilation and microvessel adenylate cyclase stimulation by synthetic parathyroid hormone-like protein fragments. Eur. J. Pharmacol. 1989b; 174: 139-151.
186. Nagataki S., Nakashima M., Akino K., et al. Parathyroid hormone-related peptide expression in endocrine tumors. Miner Electrolyte Metab 1995; 21: 148–51.
187. Nangaku M. Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure. Intern Med. 2004; 43: 9–17.
188. Nickols G.A., Nickols M.A., Helwig J.J. Binding of parathyroid hormone and parathyroid hormone-related protein to vascular smooth muscle of rabbit renal microvessels. Endocrinology. 1990; 126: 721–727.
189. Nishikawa N., Kanematsu A., Negoro H. et al. PTHrP Is Endogenous Relaxant forSpontaneous Smooth Muscle Contraction in Urinary Bladder of Female Rat. Endocrinology. 2013; 154 (6): 2058-2068.
190. Nishikawa N., Yago R., Yamazaki Y. et al. Expression of parathyroid hormone/parathyroid hormone-related peptide receptor 1 in normal and diseased bladder detrusor muscles:a clinico-pathological study. BMC Urol. 2015; 15(1): 2. DOI: 10.1186/1471-2490-15-2.191. Nishikawa Y., Wang M., Carr B.I. Changes in TGF-beta receptors of rat hepatocytes during primary culture and liver regeneration: increased expression of TGF-beta receptors associated with increased sensitivity to TGF-beta-mediated growth inhibition // Journal of Cellular Physiology. 1998; 176: 612–623.
192. Noda, M., Katoh, T., Takuwa, N., Kumada, M., Kurokawa, K., & Takuwa, Y. (1994). Synergistic stimulation of parathyroid hormone-related peptide gene expression by mechanical stretch and angiotensin II in rat aortic smooth muscle cells. Journal of Biological Chemistry.1994; 269 (27): 17911-17917.
193. Noonan W.T., Qian J., Stuart W.D., Clemens T.L., Lorenz J.N. Altered renal hemodynamics in mice overexpressing the parathyroid hormone (PTH)/PTH-related peptide type 1 receptor in smooth muscle. Endocrinology.2003; 144: 4931–4938.
194. Okada H., Dannof T.M., Kalluri R., Neilson E.G. Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol Renal Physiol.1997; 273: F563–F574.
195. Okano K., Wu S., Huang X., Pirola C.J., Juppner H., Abou-Samra A.B., Segre G.V., Iwasaki K., Fagin J.A., Clemens T.L. Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin-II and PTHrP. Endocrinology. 1994; 135: 1093–1099.
196. Okutsu H., Matsumoto S., Ohtake A. et al. Effect of tamsulosin on bladder bloodflow and bladder function in a rat model of bladder over distention/emptying induced bladder overactivity. J Urol. 2011; 186(6): 2470-7.
197. Ophascharoensuk V., Giachelli C.M., Gordon K. et al. Obstructive uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis. Kidney Int. 1999; 56: 571–580.
198. Orisio, S., Benigni, A., Bruzzi, I., Corna, D., Perico, N., Zoja, C., Benatti, L., and Remuzzi, G. Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression.Kidney Int. 1993; 43: 354–358.
199. Ortega A., Romero M., Izquierdo A. Nuria Troyano Yolanda Arce Juan Antonio Ardura Maria Isabel Arenas Jordi Bover Pedro Esbrit Ricardo J. Bosch. Parathyroid hormone-related protein is a hypertrophy factor for human mesangial cells: Implications for diabetic nephropathy. J. Cell. Physiol.2012; 227: 1980–1987. https://doi.org/10.1002/jcp.22926.
200. Ortega, A., Ramila, D., Ardura, J.A., Esteban, V., Ruiz-Ortega, M., Barat, A., Gazapo, R., Bosch, R.J., & Esbrit, P. Role of parathyroid hormone-related protein in tubulointerstitial apoptosis and fibrosis after folic acid-induced nephrotoxicity. Journal of the American Society of Nephrology, Vol. 17, № 6, (2006), pp. 1594-1603.
201. Ortega, A., Ramila, D., Izquierdo, A., Gonzalez, L., Barat, A., Gazapo, R., Bosch, R.J., Esbrit, P. Role of the renin-angiotensin system on the parathyroid hormonerelated protein overexpression induced by nephrotoxic acute renal failure in the rat. Journal of the American Society of Nephrology.2005; 16 (4): 939-949.
202. Ortiz, A., Lorz, C., Catalan, M.P., Danoff, T.M., Yamasaki, Y., Egido, J., Neilson, E.G. Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure. Kidney International, Vol. 57, № 3, (2000), pp. 969-981.
203. Osterby R., Tapia J., Nyberg G., Tencer J., Willner J., Rippe B., Torffvit O. Renal structures in type 2 diabetic patients with elevated albumin excretion rate. Acta Pathologica Microbiologica et Immunologica Scandinavica.2001; 109 (11): 751-761.
204. Ott U. Aschoff A. Pocock J. et al. DNA fragmentation in chronic glomerulonephritis: an immunohistological analysis. NephronClinPract. 2007; 105: c18–28.
205. Ozkan B., Demirkesen O., Durak H. et al. Which factors predict upper urinary tract deterioration in overactive neurogenic bladder dysfunction? Urology, 2005; 66(1): 99-104. DOI.org/10.1016/j.urology.2005.02.009.
206. Pagtalunan, M.E., Miller, P.L., Jumping-Eagle, S., Nelson, R.G., Myers, B.D., Renke, H.G., Coplon, N.S., Sun, L., & Meyer, T.W. (1997). Podocyte loss and progressive glomerular injury in type II diabetes. Journal of Clinical Investigation, Vol. 99, № 2, (January 1997), pp. 342-348.
207. Pantsulaia T. Role of TGF-beta in pathogenesis of diabetic nephropathy. Georgian Medical News.2006; 131(2): 13-18.
208. Perez-Martinez F.C., Juan Y.S., Lin W.Y. et al. Expression of parathyroid hormonerelated protein in the partially obstructed and reversed rabbit bladder. Int Urol Nephrol.2009; 41(3): 505-11.
209. Philbrick W.M., Wysolmerski J.J., Galbraith S., Holt E., Orloff J.J., Yang K.H., Vasavada R.C., Weir E.C., Broadus A.E., Stewart A.F. Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev. 1996; 76: 127–173.
210. Pirola, C.J., Wang, H-M., Kamyar, A., Wu, S., Enomoto, H., Sharifi, B., Forrester, J.S., Clemens, T.L., Fagin, J.A. Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and post-transcriptional mechanisms. J Biol Chem. 1993; 286: 1987–1994.
211. Poncelet A.C. and Schnaper H.W. (1998) Regulation of mesangial cell collagen turnover by transforming growth factor-beta1. Am. J. Physiol. 275, F458–F466.
212. Powers A.C., “Diabetes Mellitus,” in Harrison’s principles of Internal Medicine, D.L. Kasper, E. Braunwald, A.S. Fauci, S.L. Hauser, D.L. Longo, and J.L. Jamerson, Eds., pp. 2152–2180, McGRaw-Hill, New York, NY, USA, 16th edition, 2005.
213. Raison D., Coquard C., Hochane M., Jacques Steger, Thierry Massfelder, Bruno Moulin, Andrew C. Karaplis, Daniel Metzger, Pierre Chambon, Jean-Jacques Helwig, and Mariette Barthelmebs. Knockdown of parathyroid hormone related protein in smooth muscle cells alters renal hemodynamics but not blood pressure. Am J Physiol Renal Physiol.2013; 305(3): F333–F342, 2013. https://doi.org/10.1152/ajprenal.00503.2012.
214. Ramila D., Ardura, J.A., Esteban, V., Ortega, A., Ortega-Ruiz, M., Bosch, R.J, Esbrit, P. (2008). Parathyroid hormone-related protein promotes inflammation in the kidney with an obstructed ureter. Kidney International. 2008; 73(7): 835-847.
215. Rees A.J. The role of infiltrating leukocytes in progressive renal disease: implications for therapy. Nature Clinical Practice. Nephrology. 2006; 2(7): 348-349.
216. Remuzzi, G., Bertani, T. (1998). Pathophysiology of progressive nephropathies. The New England Journal of Medicine, Vol. 339, № 20, (November 1998), pp. 1448-1456.
217. Remuzzi, G., Ruggenenti, P., and Benigni, A. Understanding the nature of renal disease progression.Kidney Int. 1997; 51: 2–15.
218. Rink M., Budaus L., Schafer H., Friedrich M.G., Schlomm T., Regier M., Graefen M., Salomon G.Parathyroid Hormone-Related Protein and Granulocyte Colony-Stimulating Factor Overexpression in Poorly Differentiated Bladder Cancer Correlated with Decreasing Vigilance. Current Urology. 2009; 3(1):53-56. DOI: 10.1159/000189683.
219. Ritz E., Rychlik I., Locatelli F., Halimi S., End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions // American Journal of Kidney Diseases, vol. 34, № 5, pp. 795–808, 1999.
220. Roca-Cusachs A., DiPette D.J., Nickols G.A. Regional and systemic hemodynamic effects of parathyroid hormone-related protein: preservation of cardiac function and coronary and renal flow with reduced blood pressure. J Pharmacol Exp Ther 256: 110–118, 1991.
221. Romero M., Ortega A., Olea N., Arenas M.I., Izquierdo A., Bover J., Esbrit P., Bosch R.J. Novel Role of Parathyroid Hormone-Related Protein in the Pathophysiology of the Diabetic Kidney: Evidence from Experimental and Human Diabetic Nephropathy. Journal of Diabetes Research. Volume 2013, Article ID 162846, 6 pages. http://dx.doi.org/10.1155/2013/162846.
222. Romero, M., Ortega, A., Izquierdo, A., Lopez-Luna, P., & Bosch, R.J. (2010). Parathyroid hormone-related protein induces hypertrophy in podocytes via TGF-beta (1) and p27 (Kip1): implications for diabetic nephropathy. Nephrology, Dialysis, Transplantation. 2010; Vol. 25, № 8, pp. 2447-2457.
223. Ruiz-Ortega, M., Egido, J. (1997). Angiotensin II modulates cell growth-related events and synthesis of matrix proteins in renal interstitial fibroblasts. Kidney International, Vol. 52, № 6, (1997), pp. 1497-1510.
224. Ryan M.J., Johnson G., Kirk J., Fuerstenberg S.M., Zager R.A., Torok-Storb B.: HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney. Kidney Int 45: 48-57, 1994.
225. Safirstein R., Price P.M., Saggi S.J., Harris R.C.: Changes in gene expression after temporary renal ischemia.Kidney Int37: 1515-1521,1990.
226. Saito M., Shimizu S., Kinoshita Y. et al. Bladder dysfunction after acute urinary retention in the rats: a novel over active bladder model. Mol Cell Biochem. 2010; 333(1-2): 109-14.
227. Santos, S., Bosch, R.J., Ortega, A., Largo, R., Fernandez-Agullo, T., Gazapo, R., Egido, J., Esbrit, P. (2001). Kidney International, Vol. 60, № 3, (September 2001), pp. 982-995.
228. Sato M., Muragaki Y., Saika S., Roberts A.B., Ooshima A. Targeted disruption of TGF-1/smad 3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112:1486 –1494, 2003.
229. Saussine C., Judes C., Massfelder T., Musso M.J., Simeoni U., Hannedouche T., Helwig J.J. Stimulatory action of parathyroid hormone on renin secretion in vitro: a study using isolated rat kidney, isolated rabbit glomeruli and superfused dispersed rat juxtaglomerular cells. Clin Sci (Lond) 84: 11–19, 1993.
230. Saussine, C., Massfelder, T., Parnin, F., Judes, C., Simeoni, U., and Helwig, J.J. Renin stimulating properties of parathyroid hormone-related peptide in the isolated perfused rat kidney. Kidney Int. 1993; 44: 764–773.
231. Schordan E., Welsch S., Rothhut S., Rothhut S., Lambert A., Barthelmebs M., Helwig J.J., Massfelder T. 2004 Role of parathyroid hormone-related protein in the regulation of stretch-induced renal vascular smooth muscle cell proliferation. J Am Soc Nephrol 15:3016-25.
232. Simeoni, U., Massfelder, T., Saussine, C., Judes, C., Geisert, J., Helwig, J.J. (1994). Involvement of nitric oxide in the vasodilatory response to parathyroid hormone-related peptide in the isolated rabbit kidney. Clin. Sci., 86, 245-249.
233. Simonson M.S. Endothelins: Multifunctional renal peptides. Physiol Rev. 1993; 73: 375–411.
234. Soifer E.N., Van Why, S.K., Ganz, M.B., Kashgarian, M., Siegel, N.J., and Stewart, A.F. Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia. J Clin Invest. 1993; 92: 2850–2857.
235. Sourbier C., Massfelder T. Parathyroid hormone-related protein in human renal cell carcinoma. Cancer Lett. 2006 28; 240(2):170-82.
236. Steers W.D., Broder S.R., Persson K. et al. Mechanical stretch increases secretion of parathyroid hormone-related protein by cultured bladder smooth muscle cells. J Urol. 1998; 160(3 Pt 1): 908-12.
237. Strewler G.J., Stem P.H., Jacobs J.W. et al. Parathyroid hormonelike protein from human renal carcinoma cells structural and functional homology with parathyroid hormone. J Clin Invest. – 1987; 80: 1803–1807.
238. Strutz F., Neilson E.G.: The role of lymphocytes in the progression of interstitial disease. Kidney Int Suppl 45: S106–S110, 1994.
239. Strutz F., Okada H., Lo C.W., et al. Identification and characterization of a fibroblast marker FSP1. J Cell Biol 1995; 130: 393-405.
240. Strutz, F., Muller, G.A. (2006). Renal fibrosis and the origin of the renal fibroblast. Nephrology, Dialysis, Transplantation, Vol. 21, № 12, (2006), pp. 368-3370.
241. Strutz, F., Neilson, E.G. New insights into mechanisms of fibrosis in immune renal injury.Springer Semin Immunopathol. 2003; 24: 459–476.
242. Strutz, F., Zeisberg, M., Ziyadeh, F.N., Yang, C.Q., Kalluri, R., Muller, G.A., Neilson, E.G. (2002). Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney International, Vol. 61, № 5, (May 2002), pp. 1714-1728.
243. Sun J., Xu Y., Deng H., S. Sun, Z. Dai, Y. Sun, Involvement of osteopontin upregulation on mesangial cells growth and collagen synthesis induced by intermittent high glucose // Journal of Cellular Biochemistry, vol. 109, № 6, pp. 1210–1221, 2010.
244. Sutariya B., Jhonsa D. and Saraf M.N. (2016) TGF-?: the connecting link between nephropathy and fibrosis. Immunopharmacol. Immunotoxicol. 38, 39–49.
245. Suzuki, Y., Ruiz-Ortega, M., Lorenzo, O. et al. Inflammation and angiotensin II. Int J Biochem Cell Biol. 2003; 35: 881–900.
246. Talon, I.; Lindner, V.; Sourbier, C.; Schordan, E.; Rothhut, S.; Barthelmebs, M.; Lang, H.; Helwig, J.J.; Massfelder, T. Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo. Carcinogenesis 2006, 27, 73–83.
247. Toback F.G.: Regeneration after acute tubular necrosis. Kidney Int 41: 226-246, 1992.
248. Trizna, W., Edwards, R.M. (1991). Relaxation of renal arterioles by parathyroid hormone and parathyroid hormone-related protein. Pharmacology, 42, 91-96.
249. Tsuchiya F., Ikeda I., Kanda F., Fukuoka H. A case of bladder tumor producing granulocyte-colony stimulation factor and parathyroid hormone-related protein. Hinyokika Kiyo. 2001; 47(12): 873-6.
250. Tucci J. and Beck F. (1998) Expression of parathyroid hormon-related protein (PTHrP) and the PTH/PTHrP receptor in the rat uterus during early pregnancy and following artificial deciduoma induction. J Reprod Fertil 112: 1-10.
251. Turalic, H., Deamant, F.D., Reese, J.H. Paraneoplastic production of granulocyte colony-stimulating factor in a bladder carcinoma. Scand. J. Urol. Nephrol. 2006; 40: 429– 32.
252. Turner P.R., Mefford S., Bambino T., Nissenson R.A. Transmembrane residues together with the amino terminus limit the response of the parathyroid hormone (PTH) 2 receptor to PTH-related peptide. J Biol Chem. 1998; 13; 273(7): 3830-7.
253. Ueno M., Ban S., Ohigashi T., Nakanoma T., Nonaka S., Hirata R., Iida M., Deguchi N.: Simultaneous production of granulocyte colony-stimulating factor and parathyroid hormone-related protein in bladder cancer. Int J Urol. 2000, 7: 72-75. 10.1046/j.1442-2042.2000.00141.x.
254. Urena P., Kong X.F., Abou-Samra A.B., Juppner H., Kronenberg H.M., Potts J.T. Jr., Segre G.V. Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues. Endocrinology. 1993; 133 :617–623.
255. Urena, P., Kubrusly, M., Mannstadt, M., Hruby, M., Tan, M-M., Silve, C., Lacour, B., Abou-Samra, A-B., Segre, G.V., and Drueke, T. The renal PTH/PTHrP receptor is down-regulated in rats with chronic renal failure. Kidney Int. 1994; 45: 605–611.
256. Vaidyanathan S., Mansour P., Ueno M., Yamasaki K., Wadhwa M., Soni B.M., Singh G., Hughes P.L., Watson I.D., Sett P.: Problems in early diagnosis of bladder cancer in a spinal cord injury patient: Report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder. BMC Urology. 2002, 2: 8-10.1186/1471-2490-2-8.
257. Vaidyanathan S., McCreavy D.T., McDicken I.W. et al. Immunohistochemical study of parathyroid hormone-related protein in vesical transitional epithelium of patients with spinal cord injury. Spinal cord. 1999; 37(11): 760-764.
258. Vaidyanathan S., McDicken I.W., Mansour P. et al. Parathyroid hormone-related protein (1-34) and urothelialredifferentiation in the neuropathic urinary bladder. Spinal Cord. 2000; 38(9): 546-551.
259. Van Why S.K., Hildebrandt F., Ardito T., Mann A.S., Siegel N.J., Kashgarian M.: Induction and intracellular localization of HSP-72 after renal ischemia.Am J Physiol 263: F769-F775, 1992.
260. Varki A. Trousseau’s syndrome: Multiple definitions and multiple mechanisms. Blood. 2007; 110:1723–1729. doi: 10.1182/blood-2006-10-053736.
261. Vasavada, R.C., Garcia-Ocana, A., Massfelder, T., Dann, P., and Stewart, A.F. Parathyroid hormone-related protein in the pancreatic islet and the vascular system. Recent Prog Horm Res. 1998; 53: 305–340.
262. Vielhauer, V., Anders, H.J., Mack, M. et al. Obstructive nephropathy in the mouse: progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation of CC chemokine receptor 2- and 5-positive leukocytes. J Am Soc Nephrol. 2001; 12: 1173–1187.
263. Wang, W., Han, E. Zborowska et al., “Reduced expression of transforming growth factor ? type I receptor contributes to the malignancy of human colon carcinoma cells,” The Journal of Biological Chemistry, vol. 271, № 29, pp. 17366–17371, 1996.
264. Watson P.H., Westhusin, M.E.; and Watson, A.J., Expression of PTHrP and PTHR (PTH/PTHrP-r) mRNAs and polypeptides in bovine ovary and stimulation of bovine blastocyst development in vitro following PTHrP treatment during oocyte maturation. (2001). Obstetrics & Gynaecology Publications. 61. https://ir.lib.uwo.ca/obsgynpub/61.
265. Watson, P.H., Fraher, L.J., Hendy, G.N., Chung, U.I., Kisiel, M., Natale, B.V., Hodsman, A.B. (2000). Nuclear localization of the type 1 PTH/PTHrP receptor in rat tissues. Journal of Bone and Mineral Research, Vol. 15, № 6, (June 2000), pp. 1033-1044.
266. White, K.E., & Bilous, R.W. (2000). Type 2 diabetic patients with nephropathy showstructural-functional relationships that are similar to type 1 disease. Journal of the American Society of Nephrology, Vol. 11, № 9, (2000), pp. 1667-1673).
267. Williams E.D., Leaver D.D., Danks J.A., Moseley J.M. and Martin T.J. (1994) Effect of parathyroid hormone-related protein (PTHrP) on the contractility of the myometrium and localisation of PTHrP in the uterus of pregnant rats. J Reprod Fertil 102: 209-214.
268. Winquist R.J., Baskin E.P., Vlasuk G.P. Synthetic tumor-derived human hypercalcemic factor exhibits parathyroid hormone-like vasorelaxation in renal arteries. Biochem. Biophys. Res. Commun. 1987; 149: 227–232.
269. Wolf G., Cell cycle regulation in diabetic nephropathy, Kidney Internationa, vol. 58, № 77, pp. S59–S66, 2000.
270. Wolf G., New insights into the pathophysiology of diabetic nephrophathy: from haemodynamics to molecular pathology, European Journal of Clinical Investigation, vol. 34, № 12, pp. 785–796, 2004.
271. Wolf G., Schroeder R., Ziyadeh F.N., F. Thaiss, G. Zahner, and R.A K. Stahl, High glucose stimulates expression of p27(Kip1) in cultured mouse mesangial cells: relationship to hypertrophy, American Journal of Physiology, vol. 273, № 3, pp. F348–F356, 1997.
272. Wolf, G., Ziyadeh, F.N. Molecular mechanisms of diabetic renal hypertrophy. Kidney International, Vol. 56, № 2, (1999), pp. 393-405.
273. Wolf, G., Schroeder, R., Thaiss, F., Ziyadeh, F.N., Helmchen, U., & Stahl, R.A. (1998). Glomerular expression of p27Kip1 in diabetic db/db mouse: role of hyperglycemia. Kidney International, Vol. 53, № 4, (1998), pp. 869-879.
274. Wolzt M., Schmetterer L., Dorner G., Zelger G., Entlicher J., Kapiotis S., Eichler H.G. Hemodynamic effects of parathyroid hormone-related peptide-(1-34) in humans. J. Clin.Endocrinol. Metab. 1997; 82: 2548–2551.
275. Wu S.Z., Yang S.J., Chen H.M., Peng F.F., Yu H., Krepinsky J.C., Zhang B.F. Dual roles of parathyroid hormone related protein in TGF-?1 signaling and fibronectin up-regulation in mesangial cells. BiosciRep. 2017 Oct 27; 37(5). pii: BSR20171061. doi: 10.1042/BSR20171061.
276. Xu, Z.G., Yoo, T.H., Ryu, D.R., Cheon Park, H., Ha, S.K., Han, D.S., Adler, S.G., Natarajan, R., & Kang, S.W. Angiotensin II receptor blocker inhibits p27Kip1 expression in glucose-stimulated podocytes and in diabetic glomeruli. Kidney International. 2005; 67 (3): 944-952.
277. Yamamoto M., Harm S.C., Grasser W.A., Thiede M.A. Parathyroid hormone-related protein in the rat urinary bladder: a smooth muscle relaxant produced locally in response to mechanical stretch. Proc Natl Acad Sci USA 1992; 89(12): 5326-5330.
278. Yang R., Amir J., Liu H., Chaqour B. Mechanical strain activates a program ofgenes functionally involved in paracrine signaling of angiogenesis. Physiol Genomics. 2008; 36(1): 1-14.
279. Yang T., Hassan S., Huang Y.G., Smart A.M., Briggs J.P., Schnermann J.B. Expression of PTHrP, PTH/PTHrP receptor, and Ca(2+)-sensing receptor mRNAs along the rat nephron. Am. J. Physiol. 1997; 272: F751–758.
280. Yates A.J.P., Gutierrez G.E., Smolens P., Travis P.S., Katz M.S., Aufdemorte T.B., Boyce B.F., Hymer T.K., Poser J.W., Mundy G.R. Effects of a synthetic peptide of a parathyroid hormone–related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro in rodents. J Clin Invest. 1988; 81: 932–938.
281. Yoshida T., Suzumiya J., Katakami H., Kimura N., Hisano S., Kikuchi M., Okumura M.: Hypercalcemia caused by PTH-rP associated with lung metastasis from urinary bladder carcinoma: an autopsied case. Intern Med. 1994; 33: 673-676.
282. Yuan H.T., Li X.Z., Pitera J.E., Long D.A., Woolf A.S.: Peritubular capillary loss after mouse acute nephrotoxicity correlates with down regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1alpha. Am J Pathol 163: 2289–2301, 2003.
283. Zhuang S., Yan Y., Han J., Schnellmann R.G. (2005). p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. Journal of Biological Chemistry. 2005; 280 (22): 21036-21042.
284. Zhuang, S., Dang, Y., & Schnellmann, R.G. Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration. American Journal of Physiology. Renal Physiology. 2004; 287 (3): F365-F372.
285. Zoja, C., Morigi, M., Figliuzzi, M., Bruzzi, I., Oldroyd, S., Benigni, A., Ronco, P., and Remuzzi, G. Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins. Am J Kidney Dis. 1995; 26: 934–941.
286. Zuk A., Bonventre J.V., Brown D., Matlin K.S.: Polarity, integrin and extracellular matrix dynamics in the post-ischemic rat kidney. Am J Physiol.1998; 275: C711–C731.
287. Медведев В.Л., Курзанов А.Н. Роль паратгормон-родственного протеина в патогенезе нарушений сократительной функции мочевого пузыря. Кубанский научный медицинский вестник. 2018; 25(2): 171-177.DOI: 10.25207/1608-6228-2018-25-2-171-177.
288. Семенов Н.Н., В.С. Домбровский, С.Л. Гуторов, Д.А. Филоненко, И.Н. Соколова, М.Р. Личиницер, Степанова У.В. Экспрессия паратироид-подобного протеина и его рецептора при раке почки. Российский биотерапевтический журнал. 2012; 11(4): 63-65.
289. Семенов Р.Р., Степанова Е.В., Личиницер М.Р. Значение экспрессии интегринов av?3 и av?5,паратиреоид-подобного гормона, рецепторов к птпг и остеопонтина в развитии метастазов в кости при раке молочной железы и почки. Российский биотерапевтический журнал. 2011; 10(4): 37-41.