Научная электронная библиотека
Монографии, изданные в издательстве Российской Академии Естествознания
ANSWERS TO CASE-STUDIES
Chapter 1. GENERAL PHARMACOLOGY
1. 10 L
2. 10 l/min
3. 1236 mg
4. 4 times/day or 6 hrs is too long
5. 32 hrs
6. 115,2 mg
7. 160 mg
8. 0,003 mg/ml (3 mg/L)
Chapter 2. AUTONOMIC NERVOUS SYSTEM PHARMACOLOGY
9. Edrophonium test; Neostigmine and Corticosteroids; Thymectomy
10. An organophosphorus anticholinesterase, e.g. sarin.
11. Antimuscarinics
12. Mivacurium
13. Nothing. Fresh blood plasma
14. Atropine
15. Tubocurarine
16. Norepinephrine plus phentolamine
17. Isoproterenol
18. Timolol
«DRUGS USED TO TREAT CHF»
19. Digoxin; Atorvastatin
20. Enalapril
«ANTI-ARRHYTHMIC DRUGS»
21. Quinidine
22. Propranolol
23. Lidocaine
24. Adenosine
«ANTIANGINAL DRUGS»
25. Nitroglycerin
26. MI treatment
«ANTIHYPERTENSIVE DRUGS»
27. Discontinuance of clonidine
28. A.
29. Fainting is unrelated to his drug treatment
30. Verapamil
31. Captopril
32. Hydralazine
33. Clonidine
34. A – a; B – d; C – b; D – e; E – b; F – a; G – c; H – b; I – d; J – b
35. Hydrochlorothiazide and a b-blocker
36. Thiazide or CCB, after that the addition of an ACEI
«DIURETIC DRUGS»
37. Thiazides
38. Amiloride
39. Hydrochlorothiazide
40. Furosemide
«DRUGS USED TO TREAT GIT DISORDERS»
41. Cimetidine
42. Aluminium hydroxide
43. Metoclopramide
44. Antacids
45. Sodium bicarbonate
«DRUGS USED TO TREAT RESPIRATORY DISORDERS»
46. Add oral prednisone
47. Dextromethorphan
48. Give a parenteral corticosteroid
«DRUGS AFFECTING BLOOD»
49. Protamine sulfate
50. Clopidogrel
51. Phytonadione
52. Heparin-induced thrombocytopenia
53. Bleeding time
54. Iron
Chapter 4. CENTRAL NERVOUS SYSTEM PHARMACOLOGY
«ANESTHETICS»
55. Halothane, Dantrolene
56. Midazolam
57. Ketamine
58. Lidocaine
«SEDATIVE-HYPNOTICS»
59. Diazepam
60. Flumazenil
61. “Hangover” effects; Flumazenil; Temazepam or a “Z-drug”
«ANTICONVULSANT DRUGS. ANTIPARKINSONIAN DRUGS.»
62. Ethosuximide
63. Amantadine
64. Phenytoin
65. Valproic acid
«ANTIPSYCHOTICS. ANTIDEPRESSANTS.»
66. Neuroleptic malignant syndrome
67. MAOIs
68. Clozapine
69. Amitriptyline
70. Chlorpromazine
71. Thioridazine
72. Blockade of dopaminergic receptors
73. Tourette’s syndrome. Haloperidol
74. Lithium
75. Amoxapine
«NARCOTIC ANALGESICS»
76. b) Closed head injury
77. Pentazocine
78. Worsening of pain
79. Opioid overdose; Naloxone
«CNS – STIMULANTS»
80. Hypertension, tachycardia, seizures
81. Methylphenidate
«ALCOHOLS»
82. Diazepam
83. Disulfiram
84. May precipitate epileptic seizures; Chlordiazepoxide; vitamin B1; Acamprosate
Chapter 5. CHEMOTHERAPEUTIC DRUGS
«BETA-LACTAM ANTIBIOTICS»
85. Cefotetan
86. Cephalosporins
87. Vancomycin
88. Oxacillin
89. Oxacillin
90. Ticarcillin
«ANTIBIOTICS – PROTEIN SYNTHESIS INHIBITORS»
91. Doxycycline
92. Azithromycin
93. Erythromycin
94. Vancomycin
95. Azithromycin
96. Aminoglycoside (e.g., Gentamicin)
97. Tetracycline
98. Linezolid
«SULFONAMIDES AND URINARY ANTISEPTICS»
99. A sulfonamide
100. Nitrofurantoin
«ANTIFUNGAL DRUGS»
101. Amphotericin B
102. Fluconazole
103. Amphotericin B
104. Fluconazole
«ANTIVIRAL DRUGS»
105. Indinavir
106. Zidovudine
«DRUGS USED TO TREAT TUBERCULOSIS»
107. Rifampin
108. Streptomycin
109. Prevents some adverse effects of INH therapy
«ANTIPROTOZOAL DRUGS»
110. Primaquine
111. Metronidazole
112. Metronidazole
«ANTICANCER DRUGS»
113. Leucovorin
114. Reduce the risk/severity of chemo-induced neutropenia, and related infections
115. Cisplatin
116. Asparaginase
117. Flutamide
118. Leuprolide
Chapter 6. DRUGS AFFECTING INFLAMMATORY, IMMUNE
AND TISSUE METABOLIC RESPONSES
«NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)»
119. Indomethacin
120. Misoprostol
121. Allopurinol
122. GI distress that is almost as bad as the acute gout discomfort
123. Hepatoxicity
124. No, it’s too late. N-Acetylcysteine
«HORMONES: HYPOTHALAMIC AND PITUITARY HORMONES; THYROID AND PARATHYROID DUGS. ANTIDIABETIC AGENTS.»
125. Glyburide
126. Glyburide
127. Metformin
128. Acarbose
129. Prednisone
130. Betamethasone
131. Acarbose
132. Levothyroxine (T4)
«STEROID HORMONES»
133. Increased corticosteroid (prednisone) side effects
134. Dexamethasone
135. Ketoconazole
«DRUGS USED TO TREAT ALLERGIC DISORDERS»
136. Tubocurarine
137. Adrenaline
138. Dimenhydrinate is a H1 antihistaminic drug with potent antimuscarinic action
139. A non-sedating second generation antihistaminic like loratadine
140. Anaphylactic shock
«VITAMINS»
141. Vitamin A
142. Vitamin B6 (pyridoxine)
143. Vitamin B1 (thiamine)
«HYPOLIPIDEMIC DRUGS»
144. Lovastatin
«DRUGS AFFECTING CALCIUM METABOLISM»
145. Hyperparathyroidism
146. Calcitriol
147. Vitamin D
148. Calcium gluconate
«DRUG INTERACTIONS»
149. Risk of stroke; Yes. Fluconazole inhibits the cytochrome P450 enzyme. This increases the anticoagulant effect of warfarin. Vitamin K
150. Onset of signs and symptoms of digoxin toxicity
151. Hydrochlorothiazide
152. Nitroglycerine
153. Cefotetan or Cefoperazone
154. Increased response to NMBs
155. Rifampin is an inductor of the metabolism of contraceptive steroids
156. Gastric acid is required for the absorption of oral iron salts
157. Aspirin displaces sulfonylureas from plasma protein binding sites;
Paracetamol and ibuprofen
«POISONS AND ANTIDOTES»
158. Carbon monoxide (CO)
159. A benzodiazepine; Flumazenil
160. Blindness; Ethyl alcohol 200-400 ml 20 % per os or 5 % (with 5 % glucose) IV